Tereth wrote:

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Liberator is destroyed, the brain becomes unstable. This could be matched up with Avon's s4 behaviour (if you think he was irrational).

This has got to be one of the best rationalities for Avon's behavior. One problem how does the brain transfer itsself to Avon? It was Jenna who was scanned. Maybe Avon and Blake both tried it to see if anything would happen or maybe the brain used the defense globe to transfer to Avon? I don't know. But would it be possible for the brain to survive in a human mind.

The Altas and their slaves were humanoid in appearance, so you could assume that the mental equipment was compatible. The defence mechanism makes the best plot device for the transfer as all three were affected by it. Also, if you remember the episode, there are some shots of a strange brain-looking thing at the time!

Or did the brain run the System? Maybe it only ran part of the System maybe the Scientific part?