Helen said:
I think Avon's default would be the formal. No idea which he'd use for the situation in "Blake" as he believed the betrayal to be from someone very close indeed.
It all depends on whether the Bible has survived as a religious or even a literary text, cf. "My God, my God, why hast Thou forsaken me." In fact, religious texts are the only ones in which "thou" continues to be used in C21 English.
-(Y)